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list of experiments
Solubility book (3rd Edn)
Shuba Dumpala, Khalid Mirza
To determine the solubility of 4-chlorophenylacetic acid in acetonitrile, toluene, THF and DMSO.
[Add column with links to all the raw JCAMP-DX files AL]
While perfoming the NMR, there were some magnetic disturbances, since there were distortions in the peaks.
In the NMR test, the peaks were a little broad near the baseline. Hence, they were reprocessed in order to determine the solubility.
12:45 Labeled seven half-dram vial from 1-7.
12:50 Placed a small amount of 4-chlorophenylacetic acid in each vial.
13:00 Pipetted out 200uL of seven solvents in the vials listed below. After adding the solvent to the vials, each was vortexed for about 30s.
13:10 Placed the vials in a 100mL beaker containing a small amount of water, this beaker was left in the sonicator.
13:20 Temperature of the water in the sonicator was recorded as 30 C.
13:30 The vials were observed for crystals.
16:05 Two of the vials with Methanol and acetronitrile had to be repeated for better results.
11:46 Obtained a picture of the saturated solutions after sonication -
12:15 The vials with methanol and acetonitrile were refilled with diphenyl acetic acid this time because the 4-chlorophenyl acetic acid was exhausted. These solutions have therefore been discarded.
[if they were discarded why are there results for acetonitrile? JCB]
12:25 The vials were then placed in the sonicator
12:35 The temperature of the water in the sonicator was observed to be 28 C.
12:45 The vials were removed from the sonicator.
12:50 The vials were centrifuged.
13:00 The supernatents were collected into clean dry test-tubes from the vials by adding 0.71uM Chloroform into it.
11:50 Test-tubes 3,4,5, and 6 were tested with NMR
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