Objective


Test the solubility of 4-bromophenylacetic acid, 4-hydroxybenzaldehyde, 2,4,6-trimethoxybenzaldehyde, 2,6 dichlorophenylacetic acid, 4-nitrobenzaldehyde, 3,4-(methylenedioxy)phenylacetic acid, phenylpropiolic acid, and N-(tert-butoxycarbonyl)-L serine in THF.

Results

Spreadsheet



Discussion


Conclusion


Log


5-4-2009

Vial Label
Solute
A
4-bromophenylacetic acid
B
4-hydroxybenzaldehyde
C
2,4,6-trimethoxybenzaldehyde
D
2,6 dichlorophenylacetic acid
E
4-nitrobenzaldehyde
F
3,4-(methylenedioxy)phenylacetic acid
G
phenylpropiolic acid
H
N-(tert-butoxycarbonyl)-L serine


17:44 Three half dram vials were labeled A1, A2, and A3. 250uL of THF was pippeted into vial A1. 4-bromophenylacetic acid was added to vial A1. The vial was vortexed for 20 seconds. After several trials of adding 4-bromophenylacetic acid and vortexing for 20 seconds, the solution appeared to be saturated. The solution appeared cloudy and solid was forming at the bottom. After several minutes (before sonication), solid formed at the bottom and the solution appeared to be clear. This process was repeated for vials A2 and A3.

18:00 Three half dram vials were labeled B1, B2, and B3. 250uL of THF was pippeted into vial B1. 4-hydroxybenzaldehyde was added to vial B1. The vial was vortexed for 20 seconds. After several trials of adding 4-hydroxybenzaldehyde and vortexing for 20 seconds, the solution appeared to be saturated. The solution appeared cloudy and solid was forming at the bottom. After several minutes (before sonication), solid formed at the bottom and the solution appeared to be clear. The solution appeared cloudy and solid was forming at the bottom. This process was repeated for vials B2 and B3.

18:07 Three half dram vials were labeled C1, C2, and C3. 250uL of THF was pippeted into vial C1. 2,4,6-trimethoxybenzaldehyde was added to vial C1. The vial was vortexed for 20 seconds. After several trials of adding 2,4,6-trimethoxybenzaldehyde and vortexing for 20 seconds, the solution appeared to be saturated. The solution appeared cloudy and solid was forming at the bottom. After several minutes (before sonication), solid formed at the bottom and the solution appeared to be clear. The solution appeared cloudy and solid was forming at the bottom. This process was repeated for vials C2 and C3.

18:14 Vials A1, A2, A3, B1, B2, B3, C1, C2, and C3 were placed in a small beaker with some water. The beaker was placed in the sonicator with bath temperature of 15C. The sonicator was turned on.

18:15 Three half dram vials were labeled D1, D2, and D3. 250uL of THF was pippeted into vial D1. 2,6 dichlorophenylacetic acid was added to vial D1. The vial was vortexed for 20 seconds. After several trials of adding 2,6 dichlorophenylacetic acid and vortexing for 20 seconds, the solution appeared to be saturated. The solution appeared cloudy and solid was forming at the bottom. After several minutes (before sonication), solid formed at the bottom and the solution appeared to be clear. The solution appeared cloudy and solid was forming at the bottom. This process was repeated for vials D2 and D3.

18:24 Three half dram vials were labeled E1, E2, and E3. 250uL of THF was pippeted into vial E1. 4-nitrobenzaldehyde was added to vial E1. The vial was vortexed for 20 seconds. After several trials of adding 4-nitrobenzaldehyde and vortexing for 20 seconds, the solution appeared to be saturated. The solution appeared cloudy and solid was forming at the bottom. After several minutes, solid formed at the bottom and the solution appeared to be clear. The solution appeared cloudy and solid was forming at the bottom. This process was repeated for vials E2 and E3.

18:30 Three half dram vials were labeled F1, F2, and F3. 250uL of THF was pippeted into vial F1. 3,4-(methylenedioxy)phenylacetic acid was added to vial F1. The vial was vortexed for 20 seconds. After several trials of adding 3,4-(methylenedioxy)phenylacetic acid and vortexing for 20 seconds, the solution appeared to be saturated. The solution appeared cloudy and solid was forming at the bottom. After several minutes (before sonication), solid formed at the bottom and the solution appeared to be clear. The solution appeared cloudy and solid was forming at the bottom. This process was repeated for vials F2 and F3.

18:37 Three half dram vials were labeled G1, G2, and G3. 250uL of THF was pippeted into vial G1. phenylpropiolic acid was added to vial G1. The vial was vortexed for 20 seconds. After several trials of adding phenylpropiolic acid and vortexing for 20 seconds, the solution appeared to be saturated. The solution appeared cloudy and solid was forming at the bottom. After several minutes (before sonication), solid formed at the bottom and the solution appeared to be clear. The solution appeared cloudy and solid was forming at the bottom. This process was repeated for vials G2 and G3.

18:44 Vials A1, A2, A3, B1, B2, B3, C1, C2, and C3 were taken out of the sonicator. The bath temperature was 26C. Vials A1 and A3 did not form any solid. The other vials had solid formed at the bottom.

18:53 After observing little solid in vials D1, D2, and D3, more 2,6 dichlorophenylacetic acid was added. These vials were then vortexed for 20 seconds.

18:57 Vials D1, D2, D3, E1, E2, E3, F1, F2, and F3 were placed in a small beaker with some water. The beaker was placed in the sonicator with bath temperature of 24C. The sonicator was turned on.

19:08 Three half dram vials were labeled H1, H2, and H3. 250uL of THF was pippeted into vial H1. N-(tert-butoxycarbonyl)-L serine was added to vial H1. The vial was vortexed for 20 seconds. After several trials of adding N-(tert-butoxycarbonyl)-L serine and vortexing for 20 seconds, the solution appeared to be saturated. The solution appeared cloudy and solid was forming at the bottom. After several minutes (before sonication), solid formed at the bottom and the solution appeared to be clear. The solution appeared cloudy and solid was forming at the bottom. This process was repeated for vials H2 and H3.