Imine_synthesis

=Predicting the outcome of imine formation=

Objectives

 * 1) Determine the source of the oxygen, whether it is from the atmosphere, the ethanol, or from another location.
 * 2) Determine if similar reactions occur when different aldehydes or primary aromatic amines are used.

Tasks to do
Reaction of aniline and benzaldehyde to form benzalaniline was drawn. 94 hits were found. The third hit was a report from an experiment: Synthesis and investigation of π-conjugated azomethine self-assembled multilayers by layer-by-layer growth. This experiment contained a method for the synthesis of benzalaniline from aniline and benzaldehyde and was the basis for this synthesis in Usefulchem Exp261.
 * 1) ===Substructure search on Scifinder to be performed===
 * [remove all span tags and fix article link with DOI JCB]**
 * 1) Find the solubility of doubly aromatic imines from the literature. This is the basic [|substructure] search. (using Beilstein substructure search)
 * 2) Find the melting points of doubly aromatic imines from the literature. This is the basic [|substructure] search. (using Beilstein substructure search)
 * 3) List the aromatic aldehydes and aromatic amines in the lab.

Tasks done
 1. Substructure searches on Beilstein to be performed. The exact parameters of the query were benzaldehyde as the reactant, with the search limited to benzalaniline as a product. One article ( [| http://www.sciencedirect.com/science/article/pii/S0040403907000500]- combination 5) showed that this reaction had a 99% yield, which would not allow for the side products Evan had observed.
 * [Evan did not see a side product trying to form benzalaniline, it was for the 4-chlorobenzaldehyde derivative - see the [|ONSlit sheet] for details JCB]**