Exp070

EXP70- HaeJi Choi

=Objective= To determine the solubility of 2-chloro-5-nitrobenzaldehyde and octadecyl amine in 5 different solvents. The solvents are methanol, ethanol, THF, acetonitrile, toluene by NMR. =Procedure= Saturated solutions of 2-chloro-5-nitrobenzaldehyde and octadecyl aminewere made with methanol, ethanol, THF, acetonitrile, toluene. After the last addition of solute to the solvents, they were vortexed for 10min each to saturate the solutions. After centrifuging the vials the supernatants (100uL) were placed into NMR tubes containing 700 μl of CDCl3. Proton NMR of the solutions were obtained on a 500MHz Varian Unity Inova instrument. The solubility of the isocyanide and the amine was determined using [|SAMS]. =Results=

__2-chloro-5-nitrobenzaldehyde__ **[also take a spectrum in CDCl3 and upload to ChemSpider JCB]** __octadecyl amine__
 * 1** -methanol + 2-chloro-5-nitrobenzaldehyde
 * 2** -ethanol + 2-chloro-5-nitrobenzaldehyde
 * 3** -THF + 2-chloro-5-nitrobenzaldehyde
 * 4**-acetonitrile + 2-chloro-5-nitrobenzaldehyde
 * 5** -toluene + 2-chloro-5-nitrobenzaldehyde
 * 6** -methanol + octadecyl amine
 * 7** -ethanol + octadecyl amine
 * 8** -THF + octadecyl amine
 * 9** -acetonitrile + octadecyl amine
 * 10** -toluene + octadecyl amine